Method of reducing serum uric acid and/or increasing renal...

A - Human Necessities – 61 – K

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167/231, 167/262

A61K 31/44 (2006.01) A61K 31/00 (2006.01)

Patent

CA 2036774

4-17968/=/CGC 1470 A METHOD OF REDUCING SERUM URIC ACID AND/OR INCREASING RENAL URIC ACID CLEARANCE WITH THROMBOXANE SYNTHETASE INHIBITOR AND/OR THROMBOXANE RECEPTOR ANTAGONIST OR A COMBINATION THEREOF Abstract of the Disclosure A method of reducing serum uric acid and/or increasing renal clearance of uric acid in a mammal in need thereof comprising administering to such mammal a uricosuric effective amount of a thromboxane synthetase inhibitor, a thromboxane receptor antagonist, or both in a combined uricosuric effective amount is disclosed. Compositions having one or more of the foregoing in combination with one or more uricosurics are also set forth and included within this invention.

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