Method of inducing nucleation of a material

Details Method of inducing nucleation of a material Method of inducing nucleation of a material

F - Mech Eng,Light,Heat,Weapons

26

B

F26B 5/06 (2006.01)

Patent

CA 2640833

Methods of inducing nucleation of a material is provided. The disclosed methods comprise the steps of bringing the material to a temperature near or below a phase transition temperature and decreasing the pressure to induce nucleation of the material. The disclosed methods are useful in freeze-drying processes, particularly pharmaceutical freeze-drying processes.

L'invention concerne des procédés visant à induire la nucléation d'un matériau. Les procédés décrits comprennent les étapes consistant à porter le matériau à une température proche ou inférieure à sa température de transition de phase et à modifier la pression pour induire la nucléation du matériau. Les procédés décrits sont utiles dans des procédés de lyophilisation, notamment des procédés pharmaceutiques de lyophilisation.

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