New stable formulations of recombinant human albumin-human...

A - Human Necessities – 61 – K

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A61K 38/38 (2006.01) A61P 7/00 (2006.01)

Patent

CA 2749786

Described herein are compositions and methods for treating, preventing and ameliorating diseases and conditions characterized by a lower than normal white blood cell count, such as leukopenia and neutropenia. The compositions and methods include recombinant human albumin-human granulocyte colony stimulating factor. Pharmaceutical formulations including the recombinant fusion protein, and methods of making such formulations are also described.

L'invention concerne des compositions et des procédés pour traiter, prévenir et améliorer des maladies et des troubles caractérisés par une leucocytémie inférieure à la normale, tels que la leucopénie et la neutropénie. Les compositions et les procédés comprennent de l'albumine humaine-facteur de stimulation des colonies de granulocytes humain recombinant. L'invention concerne également des formulations pharmaceutiques comprenant la protéine de fusion recombinante, et des procédés de fabrication de telles formulations.

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