Method to develop an organized microstructure within an...

A - Human Necessities – 61 – L

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A61L 27/14 (2006.01) A61L 27/04 (2006.01) A61L 27/10 (2006.01) A61F 2/00 (2006.01)

Patent

CA 2572097

A method to facilitate the ability to engineer an organized microstructure within a monolithically homogeneous implantable biomaterial, particularly metallic alloys, is provided. By starting with an ultra-fine grained, equiaxed microstructure having an averaged linear grain size of less than 5 microns, a functionally graded microstructure is developed by establishing a temperature gradient across the cross sectional dimension. In the case of a tubular product form, this dimension would be framed by the outer and inner surfaces. By ensuring one surface is held at a substantially lower temperature than the other surface a temperature gradient is developed. The present invention also provides an implantable medical device which includes an organized microstructure. In accordance with the present invention, the organized microstructure includes a first surface region having said ultra-fine grained, equiaxed microstructure and a second surface region comprising a recrystallized, coarser grained microstructure having an average linear grain size of greater than 25 microns, wherein the first and second surface regions are separated by a transition region.

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