Imino-2 benzothiazoline derivatives, process for their...

Details Imino-2 benzothiazoline derivatives, process for their... Imino-2 benzothiazoline derivatives, process for their...

C - Chemistry, Metallurgy

07

D

167/231, 167/234

C07D 277/82 (2006.01) A61K 31/425 (2006.01) C07D 417/06 (2006.01)

Patent

CA 2005590

Compounds with the formula: Image in which R1 represents a polyfluoroalkoxy or polyfluoroalkyl radical and R2 represents a -CH2-(CH(R4))n-R3 chain in which R3 represents a dialklamino, piperidino, pyrrolidinyl-1, mercapto, acylthio, alkylthio, alkylsulfinyl or alkylsulfonyl radical, R4 represents a hydrogen atom or an alkyl radical and is not equal to 0 or 1, or the remainder of a formula: Image it being understood that the alkyl and alkoxy radicals and portions contain 1 to 4 carbon atoms in a straight or branched chain and the acyl portion contains 2 to 4 carbon atoms, as well as the salts of these compounds with a mineral or organic acid, their preparation processes and the medications containing them.

BREVET D'INVENTION DERIVES DE L'IMINO-2 BENZOTHIAZOLINE, LEURS PROCEDES DE PREPARATION ET LES MEDICAMENTS LES CONTENANT RHONE-POULENC SANTE ABREGE Composés de formule : (I) Image dans laquelle - R1 représente un radical polyfluoroalcoxy ou polyfluoro- alkyle et - R2 représente . soit une chaîne -CH2-(CH(R4))n-R3 dans laquelle R3 représente un radical dialkylamino, pipéridino, pyrrolidinyl-1, mercapto, acyl- thio, alkylthio, alkylsulfinyle ou alkylsulfonyle, R4 représente un atome d'hydrogène ou un radical alkyle et n est égal à 0 ou 1, . soit un reste de formule : Image étant entendu que les radicaux et portions alkyle et alcoxy contien- nent 1 à 4 atomes de carbone en chaîne droite ou ramifiée et les portions acyle contiennent 2 à 4 atomes de carbone, ainsi que les sels de ces composés avec un acide minéral ou organique, leurs procédés de préparation et les médicaments les contenant.

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