Compounds effecting glucokinase

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 417/12 (2006.01) A61K 31/425 (2006.01) A61K 31/426 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) A61P 3/10 (2006.01) C07C 233/81 (2006.01) C07D 213/75 (2006.01) C07D 213/82 (2006.01) C07D 213/85 (2006.01) C07D 231/40 (2006.01) C07D 233/48 (2006.01) C07D 237/20 (2006.01) C07D 237/24 (2006.01) C07D 239/42 (2006.01) C07D 241/20 (2006.01) C07D 241/26 (2006.01) C07D 261/14 (2006.01) C07D 277/46 (2006.01) C07D 277/56 (2006.01) C07D 277/82 (2006.01) C07D 285/12 (2006.01) C07D 285/125 (2006.01) C07D 285

Patent

CA 2457410

The invention relates to the use of a compound of Formula (I) or a salt, solvate or prodrug thereof, wherein R1, R2, R3, n and m are as described in the specification, in the preparation of a medicament for the treatment or prevention of a disease condition mediated through glucokinase (GLK), such as type 2 diabetes. The invention also relates to a novel group of compounds of Formula (I) and to methods for preparing compounds of Formula (I).

La présente invention concerne l'utilisation d'un composé de la formule (1) ou d'un sel, un solvate ou un promédicament de ce dernier, dans laquelle R?1¿, R?2¿, R?3¿, n et m sont tels que décrits dans la spécification, dans la préparation d'un médicament destiné au traitement ou à la prévention d'un état pathologique à médiation par la glucokinase (GLK), comme le diabète de type 2 par exemple. L'invention se rapporte également à un nouveau groupe de composés de la formule (1) et à des procédés de préparation des composés de la formule (1).

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