Antisense oligonucleotides for the inhibition of integrin...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/11 (2006.01) A61K 31/70 (2006.01) A61K 47/48 (2006.01) C07H 21/04 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2325821

The present invention relates to an antisense oligonucleotide or a derivative thereof which has a sequence that corresponds to a part of a nucleic acid which encodes an integrin .alpha.v subunit and which has the ability to induce apoptosis, the preparation and the use thereof.

La présente invention concerne un oligonucléotide antisens ou un de ses dérivés ayant une séquence correspondant à une partie d'un acide nucléique codant une sous-unité de l'intégrine .alpha.¿v? et pouvant induire l'apoptose. L'invention concerne également sa préparation et son utilisation.

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