Process for the synthesis of n-demethylated morphinane...

Details Process for the synthesis of n-demethylated morphinane... Process for the synthesis of n-demethylated morphinane...

C - Chemistry, Metallurgy

07

D

C07D 489/02 (2006.01) C07D 221/28 (2006.01)

Patent

CA 2727944

The present invention relates to a process for the preparation of an N- demethyl morphinane or a protected form thereof. In one form the preparation of the N-demethyl morphinane or a protected form thereof involves the N-demethylation of an N-methyl morphinane or protected form thereof. In particular the present process is useful in the preparation N-demethyl morphinane or a protected form thereof by N-demethylation of N-methyl morphinanes or protected forms thereof extracted from plants of the genus Papaver of the family Papaveraceae. An example of a suitable N-methyl morphinane that may be usefully subjected to the process of the present invention is thebaine.

L'invention concerne un procédé de préparation d'une morphinane N-déméthylée ou d'une forme protégée de cette dernière. Dans une forme, la préparation de la morphinane N-déméthylée ou d'une forme protégée de cette dernière implique la N-déméthylation d'une N-méthyl-morphinane ou d'une forme protégée de celle-ci. En particulier, le procédé selon l'invention est utile dans la préparation d'une morphinane N-déméthylée ou d'une forme protégée de cette dernière par N-déméthylation de N-méthyl-morphinanes, ou de formes protégées de ces dernières, extraites de plantes du genre Papaver de la famille des Papaveraceae. Un exemple d'une N-méthyl-morphinane adéquate qui peut être soumise de façon utile au procédé précité est la thébaïne.

Affiliated with

Also associated with

Rating

Process for the synthesis of n-demethylated morphinane... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the synthesis of n-demethylated morphinane..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the synthesis of n-demethylated morphinane... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1938964