C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/47 (2006.01) A61K 35/38 (2006.01) A61K 38/17 (2006.01) A61K 47/48 (2006.01) C07D 205/08 (2006.01) C07D 403/12 (2006.01) G01N 33/50 (2006.01) G01N 33/92 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2420652
The invention relates to a protein extracted from the intestines of vertebrates, which absorbs cholesterol. The protein could be identified using highly affine cross-linking compounds. The invention also relates to the use of this protein for carrying out a method for identifying a compound, which inhibits cholesterol transport in the intestines.
L'invention concerne une protéine issue de l'intestin d'animaux vertébrés, qui absorbe le cholestérol. La protéine a pu être identifiée au moyen de composés à réticulation très affines. L'invention concerne en outre l'utilisation de cette protéine par mise en oeuvre d'un procédé pour identifier un composé qui inhibe le transport du cholestérol dans l'intestin.
Glombik Heiner
Kramer Werner
Aventis Pharma Deutschland Gmbh
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Sanofi-Aventis Deutschland Gmbh
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