Pyrazole derivatives

Details Pyrazole derivatives Pyrazole derivatives

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/4412 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2603472

Compounds of the formula (I) in which R1 and R2 have the definitions specified in claim 1 are inhibitors of tyrosine kinases, especially TIE-2, and of Raf kinases, and can be used for applications including the treatment of tumours.

L'invention concerne des composés de formule (I) dans laquelle R1 et R2 ont la signification indiquée dans la revendication 1. Ces composés constituent des inhibiteurs des tyrosine kinases, notamment de TIE-2, et des Raf-Kinases. Ils peuvent être utilisés, entre autres, pour le traitement de tumeurs.

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