A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/36 (2006.01) A61P 7/04 (2006.01)
Patent
CA 2634026
The invention is concerned with the use of a peptide comprising the N-terminal sequence Gly-His-Arg-Pro-Leu-Asp-Lys-Lys-Arg-Glu-Glu-Ala-Pro-Ser-Leu-Arg-Pro-Ala-Pro--- Pro-Pro-Ile-Ser-Gly-Gly-Gly-Tyr-Arg or any allelic variant or derivative of said peptide possessing the biological property of matching the inducible VE-cadherin binding motif on the B.beta.-chain (i.e. B.beta.15-42) of human fibrin for the preparation of a pharmaceutical preparation for the treatment of shock, more specifically of hemorrhagic shock.
L'invention concerne l'utilisation d'un peptide comprenant une séquence à N terminaux Gly-His-Arg-Pro-Leu-Asp-Lys-Lys-Arg-Glu-Glu-Ala-Pro-Ser-Leu-Arg-Pro-Ala- Pro-Pro-Pro-Ile-Ser-Gly-Gly-Gly-Tyr-Arg, ou d'une variante ou d'un dérivé quelconque de ce peptide, possédant des propriétés biologiques, avec lequel des motifs de liaison de VE-cadhérine inductibles s'adaptent à la chaîne Bß (c'est-à-dire. Bß<SUB>15-42</SUB>) de la fibrine humaine, en vue de produire une composition pharmaceutique destinée à un traitement de choc, plus précisément au traitement d'un choc hémorragique.
Henning Rainer
Petzelbauer Peter
Fibrex Medical Research & Development Gmbh
Perley-Robertson Hill & Mcdougall Llp
LandOfFree
Pharmaceutical composition for treating haemorrhagic shock... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Pharmaceutical composition for treating haemorrhagic shock..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pharmaceutical composition for treating haemorrhagic shock... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1939345