Methods for the rapid expansion of antigen specific t-cells

Details Methods for the rapid expansion of antigen specific t-cells Methods for the rapid expansion of antigen specific t-cells

A - Human Necessities

61

K

A61K 39/12 (2006.01)

Patent

CA 2608193

The present invention encompasses a method for expanding an antigen specific T cell from a population of cells. The method of the present invention comprises contacting a population of cells with an MHC restricted antigenic peptide, a cytokine and a co-stimulatory signal. The invention also encompasses compositions and kits comprising an antigen specific T cell.

La présente invention concerne un procédé permettant l'expansion d'un lymphocyte T spécifique à l'antigène à partir d'une population de cellules. Ce procédé consiste à mettre en contact une population de cellules avec un peptide antigénique à restriction au CMH, une cytokine et un signal de co-stimulation. Cette invention concerne également des compositions et des kits comprenant un lymphocyte T spécifique à l'antigène.

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