Substituted imidazopyridazines and pyrrolopyrimidines as...

C - Chemistry – Metallurgy – 07 – D

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C07D 487/04 (2006.01) A61K 31/437 (2006.01) A61K 31/5025 (2006.01) A61K 31/519 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2686903

The present invention relates to compounds are of the formula I, processes for the preparation thereof, more generally these compounds for use in the treatment of the human or animal body, in the treatment of an inflammatory or obstructive airway disease, disorders commonly occurring in connection with transplantation, or a proliferative disease, which disease responds to an inhibition of kinases of the PI3-kinase-related protein kinase family.

La présente invention porte sur des composés représentés par la formule I, des procédés pour la préparation de ceux-ci, d'une façon plus générale, sur ces composés pour une utilisation dans le traitement du corps humain ou animal, dans le traitement d'une maladie inflammatoire ou d'obstruction des voies aériennes, de troubles se produisant fréquemment en ce qui concerne une transplantation ou une maladie proliférative, laquelle maladie répond à une inhibition de kinases de la famille des protéines kinases apparentées à la kinase PI3.

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