Il-2 analogs containing n-linked glycosylation sites

Details Il-2 analogs containing n-linked glycosylation sites Il-2 analogs containing n-linked glycosylation sites

C - Chemistry, Metallurgy

12

N

530/13, 195/1.32

C12N 15/26 (2006.01) C07K 14/55 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2011095

36 Title BT-0023 IL-2 Analogs Containing N-linked Glycosylation Sites Abstract of the Disclosure Biologically active analogs of human IL2, which differ from natural IL2 by the substitution of amino acid residues to form N-linked glycosylation sites in the molecule, are prepared by recombinant DNA techniques. Such analogs of IL2 are N-linked glycosylated when expressed in eukaryotic cells. Natural IL2 is not N-linked glycosylated. 36

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