Camptothecin derivatives and their uses

Details Camptothecin derivatives and their uses Camptothecin derivatives and their uses

C - Chemistry, Metallurgy

07

D

C07D 491/22 (2006.01) A61K 31/475 (2006.01) A61P 35/00 (2006.01) C07D 209/00 (2006.01) C07D 221/00 (2006.01) C07D 311/00 (2006.01)

Patent

CA 2643400

New camptothecin derivatives with the following structure of the formula (I), their use and the pharmaceutical compositions containing the same. The compounds of the present invention have good anti-tumor activities and good solubility in water, and can be used in development of medicines.

L'invention porte sur de nouveaux dérivés de la camptothécine de formule (I), sur leurs utilisations, et sur des préparations pharmaceutiques les contenant. Lesdits dérivés présentent une bonne activité antitumorale, une bonne solubilité dans l'eau, et peuvent servir à la mise au point de médicaments.

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