Nitric oxide donors for treatment of disease and injury

Details Nitric oxide donors for treatment of disease and injury Nitric oxide donors for treatment of disease and injury

A - Human Necessities

61

K

A61K 31/505 (2006.01) A61K 31/00 (2006.01) A61K 31/519 (2006.01)

Patent

CA 2471147

A method of promoting neurogenesis by administering a therapeutic amount of a phosphodiesterase inhibitor compound to a patient in need of neurogenesis promotion. A compound for providing neurogenesis having an effective amount of a phosphodiesterase inhibitor sufficient to promote neurogenesis. A phosphodiesterase inhibitor for promoting neurogenesis. A method of augmenting the production of brain cells and facilitating cellular structural and receptor changes by administering an effective amount of a phosphodiesterase inhibitor compound to a site in need of augmentation. A method of increasing both neurological and cognitive function by administering an effective amount of a phosphodiesterase inhibitor compound to a patient.

La présente invention concerne une méthode permettant de favoriser la neurogenèse par administration d'une quantité thérapeutique d'un composé inhibiteur de phosphodiestérase à un patient. L'invention concerne également un composé provoquant la neurogenèse présentant une quantité efficace d'un inhibiteur de phosphodiestérase suffisante pour favoriser la neurogenèse. L'invention concerne encore un inhibiteur de phosphodiestérase permettant de favoriser la neurogenèse. L'invention concerne aussi une méthode permettant d'augmenter la production de cellules cérébrales et de faciliter les modifications de la structure et des récepteurs cellulaires par administration d'une quantité efficace d'un composé inhibiteur de phosphodiestérase sur un site nécessitant une augmentation. L'invention concerne enfin une méthode permettant d'augmenter la fonction neurologique et cognitive par administration d'une quantité efficace d'un composé inhibiteur de phosphodiestérase à un patient.

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