Methods for magnetic resonance imaging

Details Methods for magnetic resonance imaging Methods for magnetic resonance imaging

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A61K 49/14 (2006.01) C07K 14/47 (2006.01) C07K 19/00 (2006.01) C12N 15/12 (2006.01) C12N 15/85 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2601069

In certain aspects the present invention provides methods and compositions related to contrast agents for magnetic resonance imaging. In certain variations, contrast agents provided herein are generated in situ via genetic instructions and become potent upon sequestering available metal atoms. Exemplary contrast agents include metal-binding proteins.

Dans certains aspects, l'invention concerne des procédés et des compositions en rapport avec des agents de contraste, destinés à l'imagerie par résonance magnétique. Dans certaines variations, des agents de contraste formés ici sont générés par des instructions génétiques et entrent en puissance après la séquestration des atomes de métaux disponibles. Des agents de contraste d'exemple comprennent des protéines de liaison de métaux.

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