C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/071 (2010.01) A61K 35/14 (2006.01) C07K 16/28 (2006.01) G01N 33/569 (2006.01)
Patent
CA 2279476
The present invention relates to an antibody composition which contains antibodies directed to murine leukocyte and murine erythroid cells. This composition is used in a novel negative selection process to enrich for human hematopoietic cells from a sample from human-murine chimeric mice. The invention also relates to kits for carrying out this process.
La présente invention porte sur une préparation d'anticorps, qui contient des anticorps dirigés contre des leucocytes murins et des cellules érythroïdes murines. Cette préparation est utilisée dans le cadre d'un nouveau procédé de sélection négative permettant d'enrichir des cellules hématopoïétiques humaines avec un échantillon prélevé de souris chimères humain-souris. L'invention porte également sur des trousses permettant de réaliser ce procédé.
Eaves Connie J.
Thomas Terry E.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Stemcell Technologies Inc.
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