Modulators of beta-2-adrenergic receptor for treating...

A - Human Necessities – 61 – K

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Details

A61K 31/137 (2006.01) A61K 31/135 (2006.01) A61K 31/167 (2006.01) A61K 31/535 (2006.01) A61P 9/10 (2006.01) A61P 11/00 (2006.01) A61P 19/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2672983

The invention provides medicaments comprising an agent, which selectively modulates ß2-adrenergic receptor conformation, or receptor activity, or activation thereof. The medicaments may be used for treating diseases that are characterised by disorganized and/or abnormal vasculature, such as cancer and metastatic disease. The medicaments may also be used for promoting organized/normal branched vasculature.

La présente invention concerne des médicaments comprenant un agent, qui module sélectivement une structure de récepteur ß2-adrénergique, ou une activité de récepteur, ou une activation de celui-ci. Lesdits médicaments peuvent être utilisés dans le traitement de maladies qui sont caractérisées par une vasculature désorganisée et/ou anormale, comme dans le cas du cancer et de maladies métastatiques. Lesdits médicaments peuvent également être utilisés pour favoriser une vasculature ramifiée organisée/normale.

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