Butenoic acid derivatives, processes for the preparation...

C - Chemistry – Metallurgy – 07 – C

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C07C 69/734 (2006.01) A61K 31/192 (2006.01) A61K 31/216 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) C07C 59/60 (2006.01)

Patent

CA 2534493

The present invention relates to butenoic acid derivatives of the formula (I) in which R, R1, R2 and R3 are as defined in the description, and also to processes for the preparation thereof, to pharmaceutical compositions comprising them and to their use for the treatment of dyslipidaemia, atherosclerosis and diabetes.

L'invention concerne des dérivés de l'acide buténoïque représentés par la formule (I), dans laquelle R, R?1¿, R?2¿ et R?3¿ sont tels que définis dans le descriptif, ainsi que des procédés pour la préparation de ces dérivés, des compositions pharmaceutiques comprenant ces dérivés et l'utilisation de ces dérivés dans le traitement de la dyslipidémie, de l'athérosclérose et du diabète.

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