Immunogenic peptides and their use in transplantation

A - Human Necessities – 61 – K

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Details

A61K 38/03 (2006.01) A61P 37/00 (2006.01) C07K 14/08 (2006.01)

Patent

CA 2715517

The present invention relates to the use of immunogenic peptides comprising a T-cell epitope derived from an allograft antigen and a redox motif such as C-(X)2-[CST] or [CST]-(X)2-C in the prevention and/or treatment of allograft rejection and in the manufacture of medicaments therefore.

La présente invention porte sur l'utilisation de peptides immunogéniques comprenant un épitope de lymphocyte T issu d'un antigène d'allogreffe et un motif redox tel que C-(X)2-[CST] ou [CST]-(X)2-C dans la prévention et/ou le traitement d'un rejet d'allogreffe et dans la fabrication de médicaments à cet effet.

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