Novel thiosemicarbazonethiones

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 277/54 (2006.01) A61K 31/425 (2006.01) A61K 31/435 (2006.01) A61K 31/505 (2006.01) C07D 277/60 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2121596

2121596 9407874 PCTABS00032 The invention relates to novel thiosemicarbazonethiones of formula (I) wherein R1 is lower alkyl, lower alk-2-en-1-yl or also lower alk-2-yn-1-yl, R2 and R3 are each independently of the other hydrogen or lower alkyl or, taken together, are lower alkylidene, R4 is hydrogen, lower alkyl, lower alkoxy, aryl or aryl-lower alkyl, R5 is lower alkyl, aryl, aryl-lower alkyl, unsaturated or saturated heterocyclyl-lower alkyl, or is also lower alkyloxycarbonyl-lower alkyl, and the salts thereof, to a process for the preparation of these compounds, to pharmaceutical compositions containing them, and to the use thereof as medicaments.

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