C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/19 (2006.01) A61K 38/19 (2006.01) C07K 14/52 (2006.01) C07K 16/24 (2006.01) C12N 5/16 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2242384
The present invention provides purified and isolated polynucleotide sequences encoding a human macrophage-derived C-C chemokine designated Exodus. Also provided are purified and isolated chemokine protein, fragments and polypeptide analogs thereof, antibodies thereto, and materials and methods for the recombinant production thereof. These products are useful in therapeutic, diagnostic and medical imaging applications.
La présente invention a trait à des séquences de polynucléotides purifiés et isolés, codant pour une chémokine C-C obtenue à partir de macrophages humains et appelée Exodus. L'invention concerne également une protéine de chémokine, ses fragments et analogues polypeptidiques, des anticorps de celle-ci, purifiés et isolés, ainsi que des matériaux et des procédés destinés à leur production recombinée. Ces produits sont utiles dans des applications thérapeutiques, diagnostiques et d'imagerie médicales.
Advanced Research & Technology Institute
Indiana University Foundation
Smart & Biggar
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