Diagnosis demyelinating or spongiform disease

Details Diagnosis demyelinating or spongiform disease Diagnosis demyelinating or spongiform disease

G - Physics

01

N

G01N 33/569 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2461981

A method for detecting demyelinating disease or spongiform encephalopathy in verterbrates comprising testing a biological sample obtained from the vertebrate for antibodies capable of binding to both Acinetobacter antigens and to prion antigens. This test can be combined with previously described tests involving measurement of antibodies capable of binding to myelin and/or neurofilament and or Acinetobacter antigens. A kit for performing the test is also described.

L'invention se rapporte à un procédé de détection de maladies démyélinisantes ou de l'encéphalopathie spongiforme chez les vertébrés. Ce procédé consiste à tester un échantillon biologique prélevé chez un vertébré afin de détecter des anticorps capables de se lier aux antigènes Acinetobacter et aux antigènes du prion. Ce test peut être combiné aux tests préalablement décrits consistant à mesurer des anticorps capables de se lier à la myéline et/ou aux neurofilaments et aux antigènes Acinetobacter. L'invention concerne aussi un matériel permettant de réaliser le test susmentionné.

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