Novel serine protease inhibitory protein mt0039

Details Novel serine protease inhibitory protein mt0039 Novel serine protease inhibitory protein mt0039

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) C07K 14/81 (2006.01) C07K 16/38 (2006.01) C12N 5/10 (2006.01) C12N 9/99 (2006.01) C12Q 1/02 (2006.01) C12Q 1/37 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2459272

It is intended to provide a gene and a protein participating in the control of serine protease activity and a method of efficiently evaluating an activity controlling agent for the protein. DNA having the base sequence represented by SEQ ID NO:1; a serine protease inhibitory protein encoded by the above DNA; a method of searching for a substance binding to the above protein with the use of the protein; an antisense nucleic acid to the above DNA; and an antibody specific to the above protein.

L'invention vise un gène et une protéine participant à la régulation de l'activité de sérine protéase et un procédé pour évaluer efficacement un agent régulant l'activité pour cette protéine. Elle concerne un ADN possédant une séquence de base représentée par SEQ ID NO:1, une protéine inhibitrice de sérine protéase codée par cet ADN, un procédé pour rechercher une substance se liant à la protéine susmentionnée avec l'utilisation de la protéine; un acide nucléique antisens à l'ADN susmentionné; et un anticorps spécifique à la susdite protéine.

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