C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/19 (2006.01) A61K 38/19 (2006.01) A61K 48/00 (2006.01) C07K 14/52 (2006.01) C12N 15/62 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2375617
The invention relates to compositions, methods, and gene therapy reagents to promote or to inhibit angiogenesis in the treatment of peripheral vascular or cardiovascular diseases, utilizing a chimeric molecule comprising an angiogenic factor linked to a targeting molecule that specifically binds to a vascular endothelium.
L'invention concerne des compositions, des méthodes ainsi que des réactifs de thérapie génique destinés à favoriser ou à inhiber l'angiogénèse dans le traitement de maladies vasculaires ou cardio-vasculaires périphériques, utilisant une molécule chimère comprenant un facteur angiogénique lié à une molécule de ciblage se fixant spécifiquement à un endothélium vasculaire.
Dorner Friedrich
Falkner Falko-Guenter
Levine Arnold J.
Mitterer Artur
Scheiflinger Friedrich
Baxter Aktiengesellschaft
Bcf Llp
Edwards Lifesciences Corporation
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