C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01)
Patent
CA 2630602
Compounds, compositions and methods are provided for modulating the expression of eIF4E-BP2. The compositions comprise oligonucleotides, targeted to nucleic acid encoding eIF4E-BP2. Methods of using these compounds for modulation of eIF4E-BP2 expression and for diagnosis and treatment of diseases and conditions associated with expression of eIF4E-BP2 are provided.
La présente invention concerne des composés, des compositions et des procédés pour moduler l'expression d~eIF4E-BP2. Les compositions comprennent des oligonucléotides, ciblés vers un acide nucléique codant pour eIF4E-BP2. La présente invention concerne en outre des procédés d'utilisation de ces composés pour la modulation de l'expression d~eIF4E-BP2 et pour le diagnostic et le traitement de maladies et de pathologies associées à l'expression d~eIF4E-BP2.
Bhanot Sanjay
Dobie Kenneth W.
Jain Ravi
Isis Pharmaceuticals Inc.
Smart & Biggar
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