Modified heparin cofactor ii

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

530/13, 195/1.23

C12N 15/15 (2006.01) C07K 14/81 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2028082

07-24(637)A MODIFIED HEPARIN COFACTOR II Abstract of the Disclosure A modified heparin cofactor II is disclosed, HCII(Leu444?Arg), which has substantially improved inhibitory activity against thrombin compared to native HCII or antithrombin.

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