Novel intermediates and process for the manufacture of...

Details Novel intermediates and process for the manufacture of... Novel intermediates and process for the manufacture of...

C - Chemistry, Metallurgy

07

D

C07D 471/14 (2006.01) C07D 213/61 (2006.01) C07D 213/64 (2006.01) C07D 213/643 (2006.01) C07D 213/79 (2006.01) C07D 401/06 (2006.01) C07D 405/00 (2006.01) C07D 405/04 (2006.01) C07D 409/06 (2006.01) C07D 413/06 (2006.01) C07D 417/06 (2006.01) C07D 471/04 (2006.01) C07D 473/00 (2006.01) C07D 491/04 (2006.01) C07D 491/052 (2006.01) C07D 491/14 (2006.01) C07D 491/147 (2006.01) C07D 519/00 (2006.01) C12P 17/12 (2006.01) C12P 17/16 (2006.01)

Patent

CA 2214793

This invention discloses and claims novel intermediates and procedures for the synthesis of camptothecin derivatives, such as irinotecan, and other compounds related to the synthesis of CPT-11 of formula (I). Related procedures and compounds are also disclosed, such as a novel method of making mappicine of formula (II).

Intermédiaires et procédés nouveaux pour la synthèse de dérivés de camptothécine, tels que l'irinotecan, et d'autres composés liés à la synthèse du CPT-11 de formule (I). Sont décrits également des procédés et des composés apparentés, tels qu'un procédé nouveau de fabrication de mappicine de formule (II).

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