C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 21/04 (2006.01) C12Q 1/68 (2006.01) C40B 30/04 (2006.01)
Patent
CA 2735260
The present invention provides methods for aiding in the diagnosis of the neoplastic condition of a lung cell comprising detecting the presence of an overexpressed proto-oncogene selected from the group consisting of b-myb, p67, PGP9.5 and 8- oxo-dGTPase, in a lung cell sample, wherein said presence is indicative of the neoplastic condition of the lung cell. Also provided are methods to identify potential therapeutic agents for reversal of a neoplastic condition of a lung cell where the cell is characterized by overexpression of such a proto-oncogene. Also provided are probes or primers suitable for detection of the proto-oncogene and kits for use in the diagnostic method.
Beaudry Gary A.
Bertelsen Arthur H.
Jen Jin
Madden Stephen L.
Esoterix Genetic Laboratories Llc
Fetherstonhaugh & Co.
John Hopkins University
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