Substituted pentaalkylchromans

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 311/72 (2006.01) C07C 37/16 (2006.01) C07C 39/373 (2006.01) C07D 311/58 (2006.01) C07D 311/70 (2006.01)

Patent

CA 2082004

ABSTRACT OF THE DISCLOSURE Novel substituted pentaalkylchromans of the general formula: Image (I) in which each R represents lower alkyl and Hal represents chlorine, bromine or iodine are disclosed. The compounds (I) are novel intermediates for the preparation of hypolipidaemic pharmaceuticals. A process for their preparation is described in which a trialkylhydroquinone is reacted with a halogenated butenol to give a substituted tetraalkylhydroquinone, which is then cyclised to form the final product.

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