Use of a peptide as a therapeutic agent

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/08 (2006.01) A61K 38/26 (2006.01) A61P 3/00 (2006.01) A61P 9/00 (2006.01) A61P 11/00 (2006.01) A61P 25/28 (2006.01) A61P 31/00 (2006.01) A61P 31/22 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2699177

The present invention is directed to the use of the peptide compound Ser-Gln- Ala-Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe-NH2 as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquide buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Ser-Gln-Ala-Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe-NH2 optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.

La présente invention concerne l'utilisation du composé peptidique Ser-Gln-Ala-Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe-NH2 comme agent thérapeutique pour la prévention et/ou le traitement d'un cancer, de maladies auto-immunes, de maladies fibrotiques, de maladies inflammatoires, de maladies neurodégénératives, de maladies infectieuses, de maladies pulmonaires, de maladies cardiaques et vasculaires et de maladies métaboliques. La présente invention se rapporte en outre à des compositions pharmaceutiques, de préférence sous la forme d'un lyophilisat ou d'une solution tampon liquide ou d'une formulation de lait maternel artificiel ou d'un substitut de lait maternel, contenant le peptide Ser-Gln-Ala-Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe-NH2, éventuellement en association avec au moins un support, un cryoprotecteur, un lyoprotecteur, un excipient et/ou un diluant pharmaceutiquement acceptable(s).

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