Indole derivatives and their use as 5-ht2b and 5-ht2c...

Details Indole derivatives and their use as 5-ht2b and 5-ht2c... Indole derivatives and their use as 5-ht2b and 5-ht2c...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/407 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2432085

The present invention refers to chemical compounds of formula (I), as well as pharmaceutically usable salts, solvates and esters thereof, wherein R1~ to R4~ and n have the significance given in claim (1). They can be used in the form of pharmaceutical preparations for the treatment or prevention of disorders of the central nervous system, cardiovascular disorders, gastrointestinal disorders, diabetes, obesity and sleep apnoea.

L'invention concerne des composés chimiques de formule (I), ainsi que des sels, des solvates et des esters de ces composés utilisables sur le plan pharmaceutique, dans laquelle R<1> à R<4> et n possèdent les significations données dans la revendication (1). Ces composés peuvent être utilisés sous la forme de préparations pharmaceutiques destinées au traitement ou à la prévention de troubles du système nerveux central, de troubles cardio-vasculaires, de troubles gastro-intestinaux, de diabètes, de l'obésité et de l'apnée du sommeil.

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