Wound healing and orofacial clefting

Details Wound healing and orofacial clefting Wound healing and orofacial clefting

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2363839

A nucleic acid molecule, fragment or derivative thereof which encodes a tissue repair protein wherein said isolated nucleic acid molecule, fragment or derivative thereof, has the nucleotide sequence of SEQ ID NO:1. The invention also discloses use of the protein, the production of antibodies thereto, reporter gene construct and the use of the nucleic acid, protein, antibodies and products there in diagnosing and treating orofacial clefting, tissue damage and/or for wound healing.

L'invention concerne une molécule d'acide nucléique, et un fragment ou un dérivé de celle-ci, codant pour une protéine de réparation tissulaire. Cette molécule d'acide nucléique isolé, ou le fragment ou le dérivé de celle-ci, présente la séquence nucléotidique SEQ ID NO:1. Cette invention concerne également l'utilisation de cette protéine, la production des anticorps de celle-ci, un gène rapporteur chimère, et l'utilisation de l'acide nucléique, de la protéine, des anticorps et des produits susmentionnés pour diagnostiquer et traiter le bec-de-lièvre, les lésions tissulaires, et/ou pour favoriser la cicatrisation.

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