Piperidine derivatives, their preparation and their...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/14 (2006.01) A61K 31/445 (2006.01)

Patent

CA 2107060

ABSTRACT PIPERIDINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS The invention provides a compound which is a piperidine derivative of formula (I) (I) Image in which R1 is hydrogen or straight or branched (C1-C6) alkyl, R2 is hydrogen or straight or branched (C1-C8) alkyl, Z and Z1 which may be the same or different, each is hydrogen, chlorine, hydroxyl, amino, nitro, hydroxymethyl, (C1-C2) alkyl, (C1-C8) alkoxy, straight or branched (C1-C5)alkoxycarbonyl or aryl (C1-C2) alkoxy, Z is in position 4, 6 or 7 and Z and Z1 cannot both a hydrogen, or its addition salt with a pharmaceutically acceptable acid and its therapeutic application.

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