Use of lecithin as a medicament for treating psoriasis

A - Human Necessities – 61 – K

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A61K 35/60 (2006.01) A61P 17/00 (2006.01)

Patent

CA 2606255

The invention relates to the use of lecithin or of an extract rich in lecithin for preparing a pharmaceutical composition that is useful in the prevention and therapeutic treatment of new or previous dermatites, particularly psoriasis. The invention also relates to therapeutic compositions containing lecithin or an extract rich in lecithin. According to one advantageous characteristic, the phospholipids that compose the lecithin are esterified by omega-3 polyunsaturated fatty acids, in particular, by docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA) or by an alkyl glycerol. The lecithin can be a marine lecithin , i.e. an extract of a marine organism selected among fish, shrimp, krill, zooplankton, algae, phytoplankton or a mixture thereof, of which the advantage resides in the fact that its phospholipids, particularly the phosphatidylcholine, are naturally esterified by omega-3 fatty acids, and essentially by DHA and EPA.

La présente invention se rapporte à l'emploi de la lécithine ou d'un extrait riche en lécithine pour la préparation d'une composition pharmaceutique utile dans la prévention et le traitement thérapeutique des dermatoses récentes ou anciennes, notamment du psoriasis. Les compositions thérapeutiques comprenant de la lécithine ou d'un extrait riche en lécithine sont également objet de la présente invention. Selon une caractéristique avantageuse de la présente invention, les phospholipides composant la lécithine sont estérifiés par des acides gras polyinsarurés du type oméga3, en particulier par l'acide docosahexanoïque (DHA), l'acide eicosapentanoïque (EPA), l'acide docosapentanoïque (DPA) ou par un alkyl-glycérol. La lécithine peut être une "lécithine marine" c'est-à-dire qu'elle est extraite d'un organisme marin choisi parmi les poissons, les crevettes, le krill, le zooplancton, les algues, le phytoplancton ou d'un mélange de ceux-ci, dont l'avantage réside dans le fait que ses phospholipides, notamment la phosphatidylcholine, sont naturellement estérifiés par des acides gras de type oméga3, et essentiellement par le DHA et l'EPA.

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