Spiro compounds, their production and use

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 221/20 (2006.01) A61K 31/395 (2006.01) C07D 223/14 (2006.01) C07D 241/38 (2006.01) C07D 265/34 (2006.01) C07D 401/02 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 403/06 (2006.01) C07D 409/12 (2006.01) C07D 413/02 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07D 491/10 (2006.01) C07D 491/113 (2006.01) C07D 495/10 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2143903

A compound represented by the formula: Image wherein ring A represents an optionally substituted aromatic ring; T represents an optionally substituted hydrogen atom or an optionally substituted hydrocarbon group; X represents -CH2-, -CO- or -CH(OH)-; D represents - CH2-, -O- or -NR- wherein R is a hydrogen atom or an optionally substituted hydrocarbon group and m, e and f independently represent an integer from 1 to 3, or a salt thereof, which excellently inhibits a monoamine uptake, monoamine oxidase B and/or Ca ion uptake, and is useful as a prophylactic and therapeutic drug for a central nervous diseases.

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