A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/39 (2006.01) A61K 39/145 (2006.01)
Patent
CA 2423983
The invention relates to an immunogenic complex comprising at least one glycoside and at least one lipid, integrated into an iscom complex or matrix, and at least one antigen which antigen is integrated into the iscom complex or coupled on to or mixed with the iscom complex or iscom matrix complex, characterised in that it also comprises at least one enzyme. It also relates to such a complex further comprising at least one peptide which specifically binds to a receptor expressed on a cell capable of antigen presentation, which cell expresses MHC Class I or Class II and to compositions comprising the complexes.
L'invention concerne un complexe immunologique contenant au moins un glycoside et au moins un lipide, intégré dans un complexe ou une matrice iscom, et au moins un antigène qui est intégré dans le complexe iscom ou couplé à ou mélangé au complexe iscom ou à la matrice iscom. Ce complexe immunologique est caractérisé en ce qu'il contient également au moins un enzyme. L'invention concerne également un complexe contenant au moins un peptide qui se lie spécifiquement à un récepteur exprimé sur une cellule capable de présenter un antigène. Cette cellule exprime des CMH de classe I ou classe II. L'invention concerne enfin des compositions contenant ces complexes.
Dalsgaard Kristian
Kaastrup Peter
Lowenadler Bjorn
Lycke Nils
Mc Mowat Allan
Arexis Ab
Fetherstonhaugh & Co.
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