C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) C12N 5/0783 (2010.01) A61K 39/118 (2006.01) A61K 39/40 (2006.01) C07H 21/00 (2006.01) C07K 14/295 (2006.01) C07K 16/12 (2006.01) C07K 19/00 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01) G01N 33/571 (2006.01) G01N 33/68 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2407114
Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.
L'invention concerne des composés et des procédés de diagnostic et de traitement d'une infection à Chlamydia. Ces composés renferment des polypeptides contenant au moins une portion antigénique d'un antigène de la Chlamydia et des séquences d'ADN codant pour de tels polypeptides. L'invention concerne également des compositions pharmaceutiques et des vaccins renfermant de tels polypeptides ou de telles séquences d'ADN ainsi que des anticorps dirigés contre ces polypeptides. Des kits de diagnostic contenant ces polypeptides ou ces séquences d'ADN et un réactif de détection approprié peuvent être utilisés afin de détecter l'infection à Chlamydia chez des patients et dans des échantillons biologiques.
Bhatia Ajay
Probst Peter
Stromberg Erika Jean
Corixa Corporation
Gowling Lafleur Henderson Llp
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