Sulfamoyl-containing derivatives and uses thereof

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 473/34 (2006.01) A61K 31/519 (2006.01) A61K 31/52 (2006.01) A61P 35/00 (2006.01) C07D 487/02 (2006.01)

Patent

CA 2666664

Sulfamoyl-containing compounds are disclosed, having utility as inhibitors of disease-related targets, such as Heat Shock Protein 90 (HSP90), and which are useful for treating disorders, e.g., proliferative disorders, including HSP90-mediated disorders. Methods for preparing and using the disclosed compounds are also described.

La présente invention concerne des composés contenant un sulfamoyle, présentant une utilité en tant qu'inhibiteurs de cibles liées à des maladies, comme la protéine de choc thermique 90 (HSP90), et utiles dans le traitement de troubles, par exemple de troubles prolifératifs, incluant les troubles induits par la HSP90. L'invention concerne également des procédés de préparation et d'utilisation des composés présentés.

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