Piperidine derivatives as nk1 antagonists

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 401/04 (2006.01) A61K 31/4545 (2006.01) C07D 413/04 (2006.01)

Patent

CA 2570197

A compound having the general structure shown in Formula (I) or pharmaceutically acceptable salts and/or solvates thereof are useful in treating diseases or conditions mediated by NK1 receptors, for example various physiological disorders, symptoms or diseases, including emesis, depression, anxiety and cough.

L'invention concerne un composé dont la structure générale est représentée par la formule (I) ou des sels pharmaceutiquement acceptables et solvates dudit composé, qui peuvent traiter utilement des maladies ou des états induits par les récepteurs de NK1, par exemple divers troubles physiologiques, symptômes ou maladies, dont le vomissement, la dépression, l'anxiété et la toux.

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