Oligonucleotides from sequences coding for the surface...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) A61K 31/7088 (2006.01) A61K 38/02 (2006.01) A61K 39/21 (2006.01) C07K 14/15 (2006.01) C07K 16/10 (2006.01) C12N 15/48 (2006.01) C12Q 1/70 (2006.01)

Patent

CA 2483327

The invention relates to the use of oligonucleotides from the nucleotide sequences coding for the amino-terminal region of the surface component (SU) of envelope proteins of PTLV viruses in order to perform methods of detecting every PTLV strain or PTLV-related viruses, e.g. for the detection of novel PTLV variants or viruses comprising sequences related to PTLV SUs. The invention also relates to primer pairs which are used to perform said detection methods and the novel PTLV variants thus detected.

L~invention a pour objet l~utilisation d~oligonucléotides issus des séquences nucléotiques codant pour la région aminoterminale de la composante de surface (SU) des protéines d~enveloppe des virus des PTLV, pour la mise en oeuvre de procédés de détection de toute souche de PTLV, ou de virus apparentés aux PTLV, notamment pour la détection de nouveaux variants des PTLV, ou de virus comportant des séquences apparentées aux SU des PTLV. L~invention a également pour objet des couples d~amorces pour la mise en oeuvre de ces procédés de détection, ainsi que les nouveaux variants de PTLV ainsi détectés.

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