Triazolo-pyrimidine derivatives

Details Triazolo-pyrimidine derivatives Triazolo-pyrimidine derivatives

C - Chemistry, Metallurgy

07

D

167/218, 260/242

C07D 495/14 (2006.01) A61K 31/505 (2006.01)

Patent

CA 2011325

ABSTRACT OF THE DISCLOSURE This invention relates to novel triazolo- pyrimidine derivatives of formulae (Ia) and (Ib), Image Image Ia Ib wherein Q represents hydrogen, a heterocyclic group optionally substituted by a C1-4 alkyl group and containing one or more oxygen and/or nitrogen atoms or a group of formula -SR1 wherein R1 is alkyl or aralkyl, or a group of formula -NR2R3 wherein R2 and R3 are independently hydrogen, alkyl, alkenyl, cycloalkyl, aralkyl, aryl or a heterocyclic group, m and n are independently 0, 1, 2, 3 or 4, with the proviso that if m stands for 0, then n is different from 0, and if both n and m are 1 or m stands for 0 and n is 2 then Q is different from methylthio or morpholino group, their mixtures or pharmaceutically acceptable salts. - 2 - Furthermore, the invention relates to a process for preparing these compounds. The compounds of formulae (Ia) and (Ib) are able to inhibit the ptosis caused by tetrabenazine and they have analgetic activity.

Affiliated with

Also associated with

Rating

Triazolo-pyrimidine derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Triazolo-pyrimidine derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Triazolo-pyrimidine derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1954015