Preparation of biologically active molecules

Details Preparation of biologically active molecules Preparation of biologically active molecules

C - Chemistry, Metallurgy

12

N

C12N 15/57 (2006.01) C07K 14/54 (2006.01) C07K 14/545 (2006.01) C12N 9/64 (2006.01) C12N 15/24 (2006.01) C12N 15/62 (2006.01)

Patent

CA 2368994

Biologically active molecules are produced from their biologically inactive precursors by mutation of their native cleavage site to a site which is capable of being cleaved by a protease, and cleavage of the mutated molecule to yield a biologically active molecule.

Cette invention concerne la production de molécules bioactives à partir de leurs précurseurs inactifs sur le plan biologique par mutation de leur site de coupure d'origine en un site pouvant être coupé par une protéase, puis par coupure de la molécule après mutation pour l'obtention d'une molécule bioactive.

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