Conjugates with enhanced cell uptake activity

Details Conjugates with enhanced cell uptake activity Conjugates with enhanced cell uptake activity

A - Human Necessities

61

K

A61K 47/48 (2006.01) A61P 31/18 (2006.01) A61P 35/00 (2006.01) C07K 7/06 (2006.01)

Patent

CA 2585421

This invention relates to a conjugate molecule comprising at least one first portion (I) comprising a carrier sequence and at least one second portion (II) comprising at lest one antitumot drug molecule or a protease inhibitor molecule, said conjugate molecule comprising D-enantiomeric amino acids in its portion (I). Furthermore, the invention relates to pharmaceutical compositions containing said conjugate molecule as well as to the use of said conjugate molecule for therapeutical treatment. Methods for improving cell permeability or water solubility are disclosed as well.

L'invention concerne une molécule conjuguée comprenant au moins une première partie (I) consistant en une séquence support et au moins une seconde partie (II) contenant au moins une molécule médicamenteuse antitumorale ou une molécule inhibitrice de protéase, cette molécule conjuguée contient des acides amino D-énantiomériques dans sa partie (I). En outre, l'invention concerne des compositions pharmaceutiques contenant cette molécule conjuguée ainsi que l'utilisation de celle-ci dans des traitements thérapeutiques. L'invention concerne enfin des procédé destinés à améliorer la perméabilité cellulaire ou la solubilité dans l'eau.

Affiliated with

Also associated with

Rating

Conjugates with enhanced cell uptake activity does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Conjugates with enhanced cell uptake activity, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Conjugates with enhanced cell uptake activity will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1954685