Mitotic kinesin inhibitors

Details Mitotic kinesin inhibitors Mitotic kinesin inhibitors

A - Human Necessities

61

K

A61K 31/4025 (2006.01) C07D 403/12 (2006.01)

Patent

CA 2534729

The present invention relates to dihydropyrrole compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention is also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.

L'invention concerne des composés dihydropyrrole utiles pour traiter des maladies cellulaires prolifératives et des troubles liés à l'activité kinésine KSP, ainsi que pour inhiber la kinésine KSP. L'invention concerne également des compositions comprenant ces composés ainsi que des procédés les utilisant pour traiter le cancer chez les mammifères.

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