Physiologically acceptable emulsions containing...

A - Human Necessities – 61 – K

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A61K 31/08 (2006.01) A01N 1/02 (2006.01) A01N 31/02 (2006.01) A61K 9/107 (2006.01) A61K 35/14 (2006.01) A61K 47/24 (2006.01) A61K 47/44 (2006.01) A61K 49/00 (2006.01)

Patent

CA 2188872

This invention relates to physiologically acceptable emulsions of perfluorocarbon ether hydrides having 8 to 12 carbon atoms. These novel emulsions have various medical applications. They are especially useful medically as contrast media for various biological imaging modalities such as nuclear magnetic resonance, 19F-magnetic resonance imaging, ultrasound, x-ray, and computed tomography, as oxygen transport agents or "artificial bloods" in the treatment of heart attack, stroke, and other vascular obstructions, as adjuvants to coronary angioplasty and in cancer radiation treatment and chemotherapy.

Cette invention se rapporte à des émulsions d'hydrides d'éther de perfluorocarbone ayant 8 à 12 atomes de carbone, qui sont acceptables sur le plan physiologique. Ces nouvelles émulsions possèdent diverses applications médicales. Elles sont particulièrement utiles en médecine comme milieux de contraste pour diverses techniques d'imagerie biologique, telles que la résonance magnétique nucléaire, l'imagerie par résonance magnétique ?19¿F, les ultrasons, les rayons X et la scanographie, comme agents transporteurs d'oxygène ou comme sang artificiel dans le traitement des attaques cardiaques, des accidents vasculaires cérébraux et d'autres obstructions vasculaires, comme adjuvants dans l'angioplastie coronarienne et dans le traitement des cancers au moyen de rayonnements et en chimiothérapie.

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