C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C07H 21/04 (2006.01) C12N 15/11 (2006.01)
Patent
CA 2074519
In an important embodiment, the present invention concerns a method for diagnosing compulsive disease predisposition of an individual. The method comprises initially obtaining a DNA sample of said individual and then determining the presence or absence of a particular human D2 receptor gene allele in said sample. Detection of said allele in the sample is indicative of predilection to compulsive disease. A most preferred embodiment is to detect a susceptibility to alcoholism, particularly be- cause said allele has been found to be present in a majority of clinically diagnosed alcoholics. The human D2 receptor gene A1 allele is most preferably detected in said sample.
Blum Kenneth L.
Noble E. P.
Sheridan Peter J.
Blake Cassels & Graydon Llp
Board Of Regents The University Of Texas System
The Regents Of The University Of California
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