Therapeutic agent for ischemic diseases

Details Therapeutic agent for ischemic diseases Therapeutic agent for ischemic diseases

A - Human Necessities

61

K

167/231, 260/272

A61K 31/435 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2038527

ABSTRACT Compounds of the formula: Image wherein R1 is hydrogen, lower alkyl, lower alkenyl or N,N-di(lower)alkylaminome-thyl, R2 is hydrogen, lower alkyl or halogen, R3 is imidazolyl or pyridyl, each of which may have suitable substituent(s), and R4 is hydrogen, lower alkyl, lower alkenyl or hydroxy(lower)alkyl and R5 is hydrogen, hydroxy or acyloxy, or R4 and R5 are linked together to form an additional bond, or pharmaceutically acceptable salts thereof, and their use for treating ischemic diseases. The preparation of these compounds is also disclosed as well as pharmaceutical preparations containing same.

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