Diagnostic and therapeutic cyclooxygenase-2 binding ligands

Details Diagnostic and therapeutic cyclooxygenase-2 binding ligands Diagnostic and therapeutic cyclooxygenase-2 binding ligands

A - Human Necessities

61

K

A61K 51/04 (2006.01) A61K 49/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2676413

The present invention provides conjugates useful for the diagnosis and treatment of diseases associated with the over-expression of COX-2. The conjugates comprise a selective COX-2 targeting carrier, a metal coordinating moiety, and a linker chemically linking the metal coordinating moiety to the carrier. The metals coordinated by the metal coordinating moiety are selected from paramagnetic or radioisotopes. The invention also includes kits comprising a conjugate and a radioisotope solution.

La présente invention concerne des conjugués utiles pour le diagnostic et le traitement de maladies associées à la surexpression de la COX-2. Les conjugués renferment un vecteur de ciblage de la COX-2 sélectif, une fraction de coordination de métaux et un liant destiné à lier chimiquement la fraction de coordination de métaux au vecteur. Les métaux coordinés par la fraction de coordination de métaux sont sélectionnés parmi les métaux paramagnétiques et les radioisotopes. L'invention concerne également des trousses contenant un conjugué et une solution de radioisotopes.

Affiliated with

Also associated with

Rating

Diagnostic and therapeutic cyclooxygenase-2 binding ligands does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Diagnostic and therapeutic cyclooxygenase-2 binding ligands, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Diagnostic and therapeutic cyclooxygenase-2 binding ligands will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1956157